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Clozapine and the Risk of Neutropenia: A Guide for Healthcare Providers Clozapine REMS Program Requirements for Prescribers What is the role of prescribers in the Clozapine REMS Program? Step 1: Review the full Prescribing Information for clozapine Step 2: Certify* in the Clozapine REMS Program by: Reviewing Clozapine and the Risk of Neutropenia: A Guide for Healthcare Providers Passing the Clozapine REMS Knowledge Assessment for Healthcare Providers Completing the Clozapine REMS Prescriber Enrollment Form Step 3: Enroll every new patient in the Clozapine REMS Program Step 4: Counsel each patient (or their caregiver) about the risk of severe neutropenia which clozaril for anxiety novartis clozaril clozapine n oxide clozaril history quitting clozaril clozaril can lead to serious infection Step 5: Check the ANC for each patient according to the monitoring requirement Step 6: Submit each ANC for each patient to the Clozapine REMS Program within 7/15/31 days of the lab draw date according to the patient’s monitoring frequency on the ile with the Clozapine REMS Program Step 7: Provide authorization to continue treatment, if necessary, through the Clozapine REMS Program when the patient’s ANC results meet criteria for interruption of therapy and you decide to continue clozapine treatment .
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