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[Ref] A 23-year-old female with vaginal discharge experienced fatal aplastic anemia coincident with ketoconazole (the nizoral active ingredient contained in Nizoral) therapy . An ACTH stimulation test performed 2 days later showed no evidence of underlying adrenal insufficiency when the patient was nizoral no longer being given ketoconazole .
She was admitted with widespread purpuric nizoral lesions on her face, arms, and legs .
She had taken ketoconazole 200 mg twice daily nizoral for vaginal discharge for 4 days before admission .
nizoral Ketoconazole was discontinued on admission .
The patient was diagnosed nizoral with aplastic anemia based on clinical findings .
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