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[6] tapentadol While tapentadol does not inhibit serotonin reuptake, serotonin syndrome has been reported as a severe adverse effect .
The concurrent use of medications with a serotonin-reuptake inhibition mechanism or monoamine oxidase inhibitors in combination tapentadol with tapentadol is not recommended, as it is thought that the increase in noradrenaline levels are associated with increased serotonin levels with development of serotonin syndrome without a known Tapentadol has a potential to be confused with tramadol .
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Considerations for use in palliative care Although data from phase II/III trials showed that patients in tapentadol tapentadol SR group experienced fewer adverse events than oxycodone SR, the clinical significance of this finding is unclear .
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