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Literature reports indicate that coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of LASIX (furosemide) in some patients by inhibiting furosemide prostaglandin synthesis .
Indomethacin may also affect plasma furosemide renin levels, aldosterone excretion, and renin profile evaluation .
Patients receiving both indomethacin and LASIX should be observed closely to determine if the desired diuretic and/or antihypertensive effect furosemide of LASIX is achieved .
Phenytoin interferes directly with renal action of furosemide iv administration how much furosemide can i take furosemide or lasix is used as LASIX .
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