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Case-control and cohort epidemiological studies showed that concomitant use of drugs that interfere with serotonin reuptake and an NSAID may potentiate the risk of bleeding more than Monitor patients with concomitant use of cataflam CATAFLAM with anticoagulants (e . , aspirin), selective serotonin reuptake inhibitors what is cataflam 50mg used for cataflam tabletas cataflam used for what is cataflam for cataflam 50 (SSRIs), and serotonin norepinephrine reuptake inhibitors (SNRIs) for signs of bleeding (see WARNINGS; Hematological Toxicity) . , warfarin), cataflam antiplatelet agents (e .
Clinical Impact: Controlled clinical studies showed that the concomitant use of NSAIDs and analgesic doses of aspirin does not cataflam produce any greater therapeutic effect than the use of NSAIDs alone .
In a clinical study, the concomitant use of an NSAID and aspirin was associated with a significantly increased incidence of GI adverse reactions as compared to use cataflam of the NSAID alone (see WARNINGS; Gastrointestinal Bleeding, Ulceration, and Concomitant use of CATAFLAM and analgesic doses of aspirin is not generally recommended because of the increased risk of bleeding (see WARNINGS; Hematological Toxicity) .
CATAFLAM is not a substitute for cataflam low dose aspirin for cardiovascular protection .
ACE Inhibitors, Angiotensin Receptor Blockers, and Beta-Blockers Clinical Impact: NSAIDs may diminish the antihypertensive effect of angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or beta-blockers (including In patients who are elderly, volume-depleted (including those on diuretic therapy), or have renal impairment, co-administration of an NSAID with ACE inhibitors or ARBs may result in deterioration cataflam of renal function, including possible acute renal failure .
cataflam These effects are usually reversible .
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