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Risks of Use in Patients with Gastrointestinal Conditions NUCYNTA ER tapentadol is contraindicated in patients with known or suspected gastrointestinal obstruction, including paralytic ileus .
The tapentadol in NUCYNTA ER may cause spasm of tapentadol the sphincter of Oddi .
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Monitor patients with biliary tract disease, including tapentadol acute pancreatitis, for worsening symptoms .
Increased Risk tapentadol of Seizures in Patients With Seizure Disorders The tapentadol in NUCYNTA ER may increase the frequency of seizures in patients with seizure disorders and may increase the risk of seizures in other clinical settings associated with seizures .
Monitor patients with a history of seizure tapentadol disorders for worsened seizure control during NUCYNTA ER therapy .
, buprenorphine) analgesics in patients who have received or tapentadol half life nucynta compared to methadone tapentadol is it a narcotic tapentadol are receiving a course of therapy with a full opioid agonist analgesic, including NUCYNTA ER . Avoid tapentadol the use of mixed agonist/antagonist (e . , pentazocine, tapentadol nalbuphine, and butorphanol) or partial agonist (e .
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