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Rats developed dose-related fibrotic and neoplastic changes in liver, including carcinomas, and interstitial cell tumors in sublingual nitroglycerin side effects nitroglycerin sublingual brand name can nitroglycerin stop a testes .
At high dose, the incidence of hepatocellular carcinomas in males was 48% and in females was 33% compared to nitroglycerin 0% in untreated controls .
Incidences of testicular tumors were how to make nitroglycerin nitroglycerin otc angina and nitroglycerin nitroglycerin sublingual 52% vs 8% in controls .
Lifetime dietary administration up to 1058 mg/kg/day of nitroglycerin was not tumorigenic in taking nitroglycerin when not needed nitroglycerin sublingual spray how long does a nitroglycerin mice .
Nitroglycerin was weakly mutagenic in Ames tests performed in what is the purpose of nitroglycerin when do you take nitroglycerin nitroglycerin ingredients 2 different laboratories .
Nevertheless, there was no evidence of mutagenicity in an in vivo dominant lethal assay with male rats treated with doses up to about 363 mg/kg/day, nitroglycerin PO, or in ex vivo cytogenetic tests in rat and dog tissues .
Reproductive toxicity Impairment of Fertility: In a 3-generation reproduction study, rats received dietary nitroglycerin at doses up to about 434 mg/kg/day for 6 months prior to mating of the F 0 generation with treatment continuing through successive F 1 and is medical nitroglycerin explosive define nitroglycerin nitroglycerin drug information define F 2 generations .
The high dose was associated with decreased feed intake and body nitroglycerin weight gain in both sexes at all matings .
No specific effect on the fertility of the F 0 nitroglycerin tab nitroglycerin patch 0.2 mg how to take nitroglycerin tablets benefits of generation was seen .
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