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Any drugs administered concurrently that compete for this route valtrex of elimination may increase plasma acyclovir concentrations following valaciclovir administration .
Following 1g valaciclovir, cimetidine and probenecid increase the AUC of acyclovir by this mechanism, and reduce valtrex acyclovir renal clearance .
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Pregnancy and Lactation valtrex There are limited data on the use of valaciclovir in pregnancy .
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