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Serious rash, including Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis and Drug Rash with Eosinophilia and Systemic Symptoms modalert Serious rash requiring hospitalisation and discontinuation of treatment has been reported with the use of modafinil occurring within 1 to 5 weeks after treatment initiation .
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In clinical trials of modafinil, the incidence of rash resulting in discontinuation was modalert approximately 0 . 8% (13 per 1,585) in paediatric patients (age modalert <17 years); this includes serious rash .
No serious skin rashes have been reported in adult clinical trials (0 per modalert 4,264) of modafinil .
Modafinil should be discontinued at modalert the first sign of rash and not restarted (see section 4 .
Rare cases of serious or life-threatening rash, including Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), and Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) have been reported in adults and children adrafinil recreational use modalert sun pharma buy modafinil canada buy modafinil effects time in worldwide post-marketing experience .
Because safety and effectiveness in controlled studies in children have not been established and because of the risk of serious cutaneous hypersensitivity and psychiatric adverse reactions, reduce half life of modafinil modafinil weight dosage adrafinil vs hydrafinil adrafinil alternatives the use of modafinil is not recommended Multi-organ hypersensitivity reaction Multi-organ hypersensitivity reactions, including at least one fatality in post-marketing experience, have occurred in close temporal association to the initiation of modafinil .
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