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In vitro drug metabolism studies reveal that Trazodone is a substrate of the cytochrome P450 3A4 (CYP3A4) enzyme and does trazodone 50 mg help you sleep desyrel gebelikte kullanımı desyrel withdrawal trittico opinioni Trazodone metabolism can be inhibited by the CYP3A4 inhibitors ketoconazole, ritonavir, and indinavir .
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