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The safety of fluoxetine treatment for pediatric patients has not been systematically assessed for chronic fluoxetine treatment longer than several months in duration .
In particular, there are no studies that directly evaluate the longer-term effects fluoxetine how supplied what is fluoxetine 40 mg used for fluoxetine hcl 10mg high best time to take of fluoxetine on the growth, development and maturation of children and adolescent patients .
Therefore, height and fluoxetine weight should be monitored periodically in pediatric patients receiving fluoxetine .
[see fluoxetine price fluoxetine mg size what is fluoxetine 40 mg used for fluoxetine missed dose WARNINGS AND PRECAUTIONS] .
Significant toxicity on muscle tissue, neurobehavior, reproductive organs, and bone development has been observed fluoxetine mechanism of action 80 mg fluoxetine side effects what’s fluoxetine 20 mg fluoxetine following exposure of juvenile rats to fluoxetine from weaning through maturity .
Oral administration of fluoxetine to rats from weaning postnatal day 21 through adulthood day 90 at 3, 10, or 30 mg/kg/day was associated with testicular degeneration and necrosis, epididymal vacuolation and hypospermia (at 30 mg/kg/day corresponding to plasma exposures [AUC] approximately 5-10 times the average AUC in pediatric patients at the MRHD of 20 mg/day), increased serum levels of fluoxetine creatine kinase (at AUC as low as 1-2 times the average AUC in pediatric patients at the MRHD of 20 mg/day), skeletal muscle degeneration and necrosis, decreased femur length/growth and body weight gain (at AUC 510 times the average AUC in pediatric patients at the MRHD of 20 mg/day) .
The fluoxetine names fluoxetine structure fluoxetine prescribing information fluoxetine indications what high dose of 30 mg/kg/day exceeded a maximum tolerated dose .
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