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These trends continue thus, increasing the likelihood of developing celebrex a serious GI event at some time during the course of therapy .
However, even short-term therapy is not NSAIDs should be prescribed with extreme caution in patients how much celebrex can i take celebrex purpose is celebrex an anti inflammatory drug celebrex long with a prior history of ulcer disease or gastrointestinal bleeding .
Most spontaneous reports of fatal GI events are in elderly celebrex or debilitated patients and therefore special care should be taken in treating this population .
To minimize the potential risk for an adverse GI event, the lowest effective celebrex drug study is celebrex safe 2016 celebrex 200 side effects celebrex patient teaching dose should be used for the shortest possible duration .
For high risk patients, alternate therapies that do not involve NSAIDs should be Studies have shown that patients with a prior history of peptic ulcer disease and/or gastrointestinal bleeding and who use NSAIDs, have a greater than 10-fold higher risk for developing a GI bleed than patients with celebrex neither of these risk factors .
In addition to a past history of ulcer disease, pharmacoepidemiological studies have identified several other co-therapies or co-morbid conditions that may increase the risk for GI bleeding such as: treatment with oral corticosteroids, treatment with anticoagulants, longer duration of NSAID therapy, smoking, alcoholism, older age, and poor general CLASS Study: The estimated cumulative rates at 9 months of complicated and symptomatic ulcers celebrex (an adverse event similar but not identical to the «upper GI ulcers, gross bleeding or perforation» described in the preceding paragraphs) for patients treated with CELEBREX 400 mg BID (see Special Studies – Use with Aspirin) are described in Table 5 .
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