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Recommended Dosages 2012 Induced abortion1 800µg pv or sl 3 hrly (max x3 within 12hrs)a 800µg sl single dosef 800µg pv 3 hrly (max x2) 600µg sl 3 hrly (max x2)b PPH prophylaxis2 600µg po single dosee Incomplete abortion2,3 600µg po single dosea 400µg sl single dosea Cervical ripening pre-instrumentation 400µg pv 3 hrs or sl 2-3 hrs before procedurea Induced abortion1,4 / Interruption of 400µg pv or sl 3 hrly Intrauterine foetal death4 13-17 wks 200µg pv 6 hrly (max x4)c Intrauterine foetal death4 18-26 wks 100µg pv 6 hrly (max x4)c Intrauterine foetal 25µg pv 6 hrly or Induction of labour2,5 25µg pv 6 hrly or Care with previous uterine scar and caesarean section Check for updates at misoprostol www . org 1 Only use where legal and with mifepristone, where available 2 Included in the WHO Model List of Essential Medicines 3 Leave to work for 1-2 weeks unless excessive bleeding or infection mifepristone or misoprostol misoprostol to induce miscarriage misoprostol induction misoprostol oral 4 Halve dose if previous caesarean section or uterine scar 5 Make sure you use the correct dosage – overdose can lead to complications .
Do not use if previous caesarean misoprostol section a WHO/RHR .
Safe abortion: technical and policy guidance for health systems what is misoprostol used for what is mifepristone and misoprostol how to use misoprostol alone for (2nd edition), 2012 b Gemzell-Danielsson et al .
IJGO, 2007 c Gómez Ponce de misoprostol and pregnancy other names for misoprostol how much misoprostol to take for abortion León et al .
IJGO, 2007 d WHO recommendations for induction of labour, 2011 e FIGO Guidelines: Prevention of PPH with misoprostol misoprostol, 2012 f FIGO Guidelines: Treatment of PPH with misoprostol, 2012 Abbreviations pv – vaginal; sl – under the tongue; po – oral; PPH – post-partum haemorrhage; µg – microgramme .
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